Postdoctoral Positions List

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posted on	investigator	laboratory focus	position description	contact
10/29/2024	Matthew Wortham, PhD	We study how insulin-producing cells sense and respond to their environment. Our research is focused on how environmental signals lead to transcriptional responses and functional adaptations in health and in conditions associated with diabetes.	The Wortham lab is recruiting a postdoctoral trainee to study how nutrient metabolism interfaces with the epigenome to govern adaptive and maladaptive responses by pancreatic beta cells. Successful candidates will employ combinations of stable isotope tracing, single cell genomics, and physiological studies in mouse models of diabetes and in primary human islets. Trainees in the lab will benefit from strong technical support including animal surgery, tagging, and genotyping, as well as computational analysis. This position will provide opportunities for career development activities pursuant to the trainee’s goals including presentations at regional and national conferences, networking and collaboration opportunities, and focused training in scientific communication including grantsmanship, manuscript preparation, and public speaking. Prior experience in mouse genetics and strong written communication skills are required. Experience analyzing genomic datasets is preferred.	matthew.wortham@cuanschutz.edu
10/28/2024	Christian Mosimann, PhD	Developmental mechanisms of cardiovascular development & disease and mesodermal cell fate patterning; zebrafish as principal model.	To expand our team at CU Anschutz, Section of Developmental Biology, we are looking to recruit postdocs (fully funded positions). Our research aims to elucidate the mechanisms of cell fate determination in cardiovascular development and disease. As main paradigm, we study the developmental patterning of the lateral plate mesoderm (LPM), the elusive joint origin of the cardiovascular, blood, kidney, and limb lineages. A special interest are gene-regulatory mechanisms of congenital cardiac, endothelial, and hematopoietic disease. We study this biology using advanced transgenic approaches, gene-regulatory element discovery, CRISPR-Cas9-based genome editing, and light sheet imaging using the zebrafish as principal model. In addition, we have been developing leading transgenic and genome-editing tools for zebrafish to drive our research forward. Our work intersects development, evo-devo, and disease modeling projects that we pursue with a collaborative, interactive team.	christian.mosimann@cuanschutz.edu
10/28/2024	Alexa Burger	My lab studies early notochord formation and intervertebral disc development using zebrafish and mice. We are interested in studying associated structural birth defects, intervertebral disc diseases, such as disc degeneration, and cancer.	My lab at the University of Colorado Anschutz Medical Campus is looking for motivated molecular biologists to join us as postdoctoral research fellow! We have several open positions! * Job responsibilities: - Project lead for several ongoing research projects, including design of experimental setup, data generation, data interpretation, manuscript writing - Projects range from dev bio to small molecule applications in vivo * Job qualifications: - Solid molecular and developmental biology expertise - Animal model experience, preferably mouse and zebrafish - Microscopy skills, preferably lightsheet, confocal, dissecting - Experience with small molecule/drug applications - Excellent verbal and written communication skills * Why join us? - Cutting edge research lab at Anschutz Medical Campus, Colorado - Lively lab atmosphere and high quality trainee mentoring - Numerous opportunities for collaborative, interdisciplinary research projects - Latest animal facilities and imaging setups	alexa.burger@cuanschutz.edu
10/24/2024	Ulli Bayer	Our lab studies synaptic plasticity (especially LTP and LTD), with a focus on CaMKII. We are interested in the molecular mechanisms of physiological plasticity and how this goes wrong in pathological situations . Pubmed: Bayer KU	Ideally with experience in electrophysiology and/or rodent behavior. Experience in biochemistry or imaging also considered.	ulli.bayer@cuanschutz.edu
10/24/2024	Heide Ford	The Ford lab studies cancer cell plasticity with an emphasis on transcriptional and translational control of plasticity, and how that contributes to tumor progression and metastasis. We examine plasticity in cancer cells and in the immune cells.	The postdoc applicant would be able to work on any of a number of projects which span tumor types (both adult and pediatric cancers) with a focus on either transcriptional or translational control of tumor cell plasticity. The postdoc would also be able to work on the immune microenvironment, where our focus currently is mostly on the pre-metastatic and metastatic niche, and alterations to the innate immune system in response to the tumor. Our laboratory focuses on understanding basic molecular mechanisms of tumor progression using cutting edge technologies including (but not limited to) CUT&RUN, ATAC-seq, bulk and sc-RNA seq, and ribo-seq, and we also move from in vitro to in vivo using both zebrafish and mouse models.
10/24/2024	Cecilia Caino	We study the impact of organelle dynamics and cell signaling in cancer progression, with the long term goal of identifying novel anti-metastatic therapeutic targets.	Open to postdoc inquiries. The goal of our research is to understand how mitochondria participate in cellular signaling pathways that are exploited in metastatic cancers. Research will involve biochemistry, molecular biology and cellular biology experimental procedures, high-throughput loss-of-function screenings and work with animal models of cancer and metastatic dissemination. Best matches would have recently graduated with a PhD in cellular biology, molecular biology or similar field, and come with experience in animal models of cancer. In addition to research, fellows will submit their applications for funding , train more junior members of the lab, and co-craft a career development plan tailored to their interests and goals with the help of the PI.	cecilia.caino@cuanschutz.edu
10/18/2024	Debosmita Sardar	We study glial cells – the non-neuronal cells in the brain. More specifically, our lab is interested in the question of how glia and epigenetics shape sense of smell. For more details, visit external link	A postdoctoral fellow full-time position is available in Dr. Debo Sardar’s lab at the Department of Pharmacology at Anschutz Medical Campus. Using transgenic mouse models, our approaches include molecular neuroscience, cellular neuroscience and systems neuroscience, with the primary goal of understanding how glial epigenetics shape sense of smell. You will be working in an environment conducting new neuroscience research in the areas of sensory biology (systems neuroscience), glial biology (cellular neuroscience), and epigenomics (molecular neuroscience). Given the broad range of the research spanning from systems to cells to genes, you will gain exposure to a diverse array of concepts and technologies. Dr. Debo Sardar highly values mentoring and is dedicated to help you achieve your independent goals.	debosmita.sardar@cuanschutz.edu
10/16/2024	Elizabeth J Kovacs, PhD	Inflammation and innate immunity in the context of tissue injury and repair. Gut-lung axis and gut-brain axis	A post-doctoral position is available in the laboratory of Elizabeth J. Kovacs, PhD in the Department of Surgery at the University of Colorado Denver Anschutz Medical Campus. The laboratory works on multi-organ system inflammatory response and innate immunity in the context of trauma and infection. Recent studies have focused on the effects of alcohol intoxication, advanced age, sex differences and infection on the initiation and resolution of inflammation in both in vivo murine models and clinical samples.	Natalie.deschaine@cuanschutz.edu
10/10/2024	Stephanie Wesolowski	Fetal metabolic physiology and developmental programming	Current studies in our research program are focused on understanding the mechanisms for the early activation of fetal hepatic glucose production and development of hepatic insulin resistance, specifically the role of reduced glucose versus oxygen supply to the fetus, both key features of placental insufficiency and resulting fetal growth restriction (FGR). This is important in understanding why FGR offspring have increased susceptibility to diabetes across their lifespan. We also have projects investigating the effects of maternal high fat diet and obesity on offspring metabolism, specifically the early development of hepatocellular injury, including fibrosis and steatosis, and immune cell reprogramming. New projects are also investigating the effects of metformin exposure on the developing fetal liver and the postnatal consequences.	Email CV and interest letter to stephanie.wesolowski@cuanschutz.edu
10/09/2024	Russ Glasgow and Dan Matlock	This comprehensive patient-centered personalization program will develop patient-centered decision support tools across various clinical domains, with a strong emphasis on rapid and rigorous development, sustainable processes and equity in engagement	A two-year postdoctoral fellowship opportunity is available at the University of Colorado Anschutz Medical Campus. This is a unique position that will help to integrate work across the Dissemination and Implementation Science Program (external link led by Russ Glasgow, PhD and the Colorado Program for Patient Centered Decisions (CPPCD) led by Dan Matlock, MD. Both are part of the Adult & Child Consortium for Health Outcomes Research & Delivery Science (ACCORDS). The successful applicant will work as part of a multidisciplinary team of established researchers focused on shared decision making, patient centered care, implementation science, and pragmatic research. The candidate will be an integral part of a new initiative to conduct and support research that is rapid, rigorous, and relevant to patients and a variety of diverse clinical settings.	Kate Noonan, MSW kate.noonan@cuanschutz.edu Research Services Manager Colorado Center for Patient Centered Decisions Adult and Child Center for Outcomes Research and Delivery Science (ACCORDS) University of Colorado School of Medicine \| Children’s Hospital Colorado Mailstop F443 \| 1890 North Revere Court \| Aurora, CO 80045 C 303.618.2181 \| F 303.724.1839
10/08/2024	Seth Creasy, PhD	We focus on how manipulations in diet, physical activity, and sleep affect energy metabolism in humans. We have recently been focused on how the timing of these behaviors alter body composition, energy balance regulation, and other 24-hour behaviors.	We are seeking a postdoctoral fellow generally interested in understanding how lifestyle behaviors (diet, physical activity, and sleep) affect cardiometabolic health. Individuals with doctoral degrees in physiology, nutrition, metabolism, or other related areas will be considered. We are currently looking for candidates interested in understanding how the timing of exercise alters energy metabolism using methods that span the translational spectrum. Expertise or experience with metabolic clinical research is desired. Fellows will receive training and mentorship from a team of mentors with expertise in metabolism research and will generate independent data to assist with fellowship applications. Fellows will be expected to assist with on-going projects, write grants, lead manuscripts, and lead an independent project that fits within the lab's mission.	seth.creasy@cuanschutz.edu
10/07/2024	Milton Pividori, PhD	Our lab (pivlab.org) designs machine-learning methods for human disease research using a systems biology approach to advance precision medicine through multi-omics. We emphasize open science, reproducible research, and clinical collaboratiion.	The lab is hiring a full-time Postdoctoral Fellow in computational biology with expertise in machine learning model design and biomedical applications. The ideal candidate will have experience in human genetics and genomics, multi-omics data analysis, and software development (Python/R). Responsibilities include conducting research to develop and apply machine learning models to large multi-omics datasets, writing software, collaborating locally and internationally, and mentoring students. The fellow will present findings, write manuscripts, and seek fellowship awards. The position emphasizes professional development through networking, career seminars, and creating an Individual Development Plan (IDP). Diverse applicants are encouraged to apply. Key fields include machine learning, data science, human genetics, and computational biology.	miltondp@pivlab.org
10/07/2024	Uwe Christians, MD, PhD	Clinical and biochemical pharmacology and toxicology	iC42 Clinical Research and Development (Department of Anesthesiology) is looking for highly motivated post-doctoral fellows with an interest in and passion for mass spectrometry-based bioanalytics, pharmacokinetics, drug metabolism and toxicology. The goal of the available projects is to assess the metabolism of drugs (e.g. cannabinoids, terpenes, mTOR inhibitors), to isolate and structurally identify the metabolites using ion trap and high resolution mass spectrometry as well as NMR spectroscopy, to isolate the metabolites and study their biological activities, to develop and validate quantitative LC-MS/MS assays, to assess the metabolites’ PK in vivo, and to study their pharmacodynamic/ toxicodynamic effects using a multi-omics approach (metabolomics, lipidomics, proteomics). While a background in mass spectrometry and bioanalytics is welcome, we will be glad to train the applicant in these technologies. Foreign nationals are welcome to apply.	uwe.christians@cuanschutz.edu
10/07/2024	Postdoctoral Fellowship in Psychosocial Oncology	The Psychosocial Oncology Postdoctoral Fellowship is comprised of three primary components including; clinical training, didactic education in clinical health psychology, and scholarly research and/or program development/evaluation.	Clinical activities at the University of Colorado Hospital, CU Medicine ambulatory specialty clinics on the Anschutz Medical Campus and via telehealth are designed to prepare trainees for specialty clinical practice in psychosocial oncology by practicing in different modalities including individual counseling, assessment, group therapy, inpatient consultation-liaison, and psychoeducational group classes. Additionally trainees will receive mentorship in psychosocial oncology research specific to underrepresented populations and other areas of clinical interest. Trainees will also have the opportunity to participate in didactic education, clinical research, quality improvement initiatives, and examination and board preparation for the Professional Practice in Psychology (EPPP) and the American Board of Professional Psychology (ABPP).	Applications are due December 1st. Visit external link for additional information.
10/07/2024	Ian M. Cartwright, PhD	The Labortory has a focus on furthering our understanding of the inflammatory microenvironment in the context of inflammatory bowel disease. We are specificially focused on investigating neutrophil-epithelial interactions.	This position includes bench research and project development. The project topic is: “Control of Inflammatory Acidity in Mucosal Inflammation”. Key Responsibilities: - designing, planning, and executing experiments to better understand how changes in tissue metabolism influence inflammation within the mucosa, including, but not limited to, models of inflammatory bowel disease. - utilizing specialized knowledge and sophisticated research techniques examining inflammation-related signaling by intestinal epithelial cells, with a focus on the influence of microbial-derived metabolites, esp. indoles and short chain fatty acids. - implementation of schedule methodology, timeline and lab book - collecting, recording, analyzing, and presenting data - preparation of project reports and manuscripts for publication - meeting with the project Principal Investigators (Ian M. Cartwright and Sean P. Colgan, PhD) on a daily to weekly basis for the purpose of progress updates and mentoring	Ian.Cartwright@cuanschutz.edu
09/12/2024	Katharina Hopp, PhD	Dr. Hopp’s laboratory studies the pathomechanisms driving Autosomal Dominant Polycystic Kidney Disease (ADPKD). ADPKD is the most common monogenic renal disease worldwide.	We are interested in studying the role of the microenvironment, specifically immune cells, in ADPKD progression and apply the knowledge gained from the cancer field to PKD to develop novel interventional strategies. Key Responsibilities: • Utilize mouse/rat models for mechanistic research and preclinical intervention studies. • Perform basic cellular/molecular techniques that drive hypothesis-based research • Develop independent projects leading to grants, posters, manuscripts. • Condense, analyze, present, and write-up project results. • Supervise and work alongside graduate students and research technicians within the Hopp lab.	Betsy Pike, Renal Division Human Resources, betsy.pike@cuanschutz.edu
05/06/2024	Darleen Sandoval	The Sandoval lab uses genetic mouse models and in vivo physiological approaches to study the role of the gut-brain axis in regulating metabolism.	2023 was a break-through year for obesity treatment. In addition to bariatric surgery, we now have obesity multiple drugs that are reaching the efficacy of bariatric surgery and multiple more promising drugs in the pipeline. Like bariatric surgery, these drugs target the gut-brain axis. The Sandoval lab uses genetic mouse models, chemogenetic and in vivo physiological strategies to study the role of the gut-brain axis in regulating body weight, feeding, and metabolism. Dr. Sandoval and the postdoctoral candidate will work together to develop an individualized training plan aimed at advancement of the candidates technical and professional skillsets in order for the candidate to achieve their professional career goals whether that is to obtain a position in the academic or industry settings. Our research requires a team approach, and we are looking for someone who is interested in being a part of a diverse and productive team. external link	darleen.sandoval@cuanschutz.edu
05/06/2024	Charles Sagerstrom	Transcriptional and epigenetic control of cell fate decisions during embryonic development	During embryogenesis, the developing embryo goes through numerous transitions as new tissues, organs and cell types are formed. Each such transition is driven by a change in gene expression that can go awry and cause birth defects. We are interested in understanding how transcription factors and chromatin regulators drive gene expression programs to support the formation of new cells and tissues, using zebrafish as a model. Our group is looking for postdoctoral fellows to join our work using bioinformatics, imaging and genetic/genomic tools (scRNAseq, scATACseq, CRISPR, transgenesis) to unravel the control of cell fate decisions. Lab website: external link . Recent manuscript: doi.org/10.7554/eLife.87772..	Charles.sagerstrom@cuanschutz.edu
04/23/2024	Mark Dell'Acqua	The Dell'Acqua lab studies receptor and ion channel signaling complexes regulating neuronal plasticity underlying normal learning and memory as well as cognitive dysfunction associated with neurodevelopmental and neurodegenerative diseases.	Open to postdoc inquiries. Applicants should have a PhD in neuroscience, pharmacology, cell biology, biochemistry or a related field. Prior experience in electrophysiology and/or fluorescence imaging is a plus but not required. Solid publication record is desired, with good written and verbal communication skills in English. Ongoing research projects focus on characterizing the role of postsynaptic scaffold proteins, kinases and phosphatases in regulating glutamate receptors, GABA receptors, and voltage-gated Ca+ channels during synaptic plasticity. Additional projects focus on how neuronal excitation is coupled to transcription to control gene expression. We are studying the function of these molecular and cellular mechanisms during normal synaptic plasticity as well as how dysfunction in these pathways contributes to nervous system disorders, including autism, intellectual disability, Alzheimer's disease, and vascular dementia.	mark.dellacqua@cuanschutz.edu
01/11/2023	Nancy F. Krebs	Nutrition – NIH T32 Research Fellowship T32DK007658-33	Individuals who have completed residency training, PhD or other terminal degree may apply for a research fellowship in nutrition. The objective of this program is to provide research training in the nutritional sciences to physician scientists, basic researchers, and behavioral scientists who are committed to prevention of disease and health promotion through careers in human nutrition. Nutrition Training Faculty provide the foundation of nutrition research. Areas of interest include obesity and energy balance; behavioral research related to eating & obesity; health promotion & nutrition education; implementation science; molecular, genetic, and environmental basis of insulin resistance and Type 2 diabetes; micronutrient homeostasis and effects of nutrient deficiency states; global nutrition; maternal and fetal nutrient utilization; fetal origins of adult disease, human aging; and the epidemiology of nutrition-related conditions	carolyn.doyle@cuanschutz.edu 303-724-5850