Job Description
iC42 Clinical Research and Development (Department of Anesthesiology) is looking for highly motivated post-doctoral fellows with an interest in and passion for mass spectrometry-based bioanalytics, pharmacokinetics, drug metabolism and toxicology. The goal of the available projects is to assess the metabolism of drugs (e.g. cannabinoids, terpenes, mTOR inhibitors), to isolate and structurally identify the metabolites using ion trap and high resolution mass spectrometry as well as NMR spectroscopy, to isolate the metabolites and study their biological activities, to develop and validate quantitative LC-MS/MS assays, to assess the metabolites’ PK in vivo, and to study their pharmacodynamic/ toxicodynamic effects using a multi-omics approach (metabolomics, lipidomics, proteomics). While a background in mass spectrometry and bioanalytics is welcome, we will be glad to train the applicant in these technologies. Foreign nationals are welcome to apply.